Post
1556
🐦 Do you remember IBIS? Not a fancy bird but the open challenge in Inferring Binding Specificities of unexplored human transcription factors. Check our site (https://ibis.autosome.org/) and have a sip of fresh news below.
👥 More than 100 teams registered for the challenge yet only two dozen are using the opportunity to explore their models on the Leaderboard. Don't miss the chance to participate in the Leaderboard stage, although independently of that you can submit the final solution.
🌐 Remember, the training data for Leaderboard and Final are available online, and you are free to mix-and-match it in any combination.
🌌 For Leaderboard, we have received 650 total submissions of AAA (advanced ML) and 296 PWM models (a whopping set of 6682 PWMs in total).
🚀 For PWMs, the baseline is left far behind, but some TFs remain tough nuts to be cracked (see the attached figure 1).
📈 For AAAs, there is a solid improvement over the best-submitted PWMs in A2G, but the G2A discipline remains unpopular (see the attached figure 2). Free hint: this is your chance!
💡 Another free hint: If your model tends to overfit given a limited set of data for some TFs don't forget to use reverse-complement and shift augmentations. Also, don't hesitate to use multitarget models i.e. predicting the binding of multiple TFs at the same time.
💡 Last but not least, try to combine knowledge from all accessible experiment types, especially for G2A discipline (ChIP-Seq & genomic HT-SELEX) in a single model!
📣 Finally and importantly, following the requests from the community, we decided to EXTEND the Leaderboard until the final submission deadline.
🗓️ The final submission deadline is also EXTENDED until Aug 15. The final submission form and details will be posted on the IBIS website in the first half of July, follow our Telegram group and mailing list (see the links at https://ibis.autosome.org).
👥 More than 100 teams registered for the challenge yet only two dozen are using the opportunity to explore their models on the Leaderboard. Don't miss the chance to participate in the Leaderboard stage, although independently of that you can submit the final solution.
🌐 Remember, the training data for Leaderboard and Final are available online, and you are free to mix-and-match it in any combination.
🌌 For Leaderboard, we have received 650 total submissions of AAA (advanced ML) and 296 PWM models (a whopping set of 6682 PWMs in total).
🚀 For PWMs, the baseline is left far behind, but some TFs remain tough nuts to be cracked (see the attached figure 1).
📈 For AAAs, there is a solid improvement over the best-submitted PWMs in A2G, but the G2A discipline remains unpopular (see the attached figure 2). Free hint: this is your chance!
💡 Another free hint: If your model tends to overfit given a limited set of data for some TFs don't forget to use reverse-complement and shift augmentations. Also, don't hesitate to use multitarget models i.e. predicting the binding of multiple TFs at the same time.
💡 Last but not least, try to combine knowledge from all accessible experiment types, especially for G2A discipline (ChIP-Seq & genomic HT-SELEX) in a single model!
📣 Finally and importantly, following the requests from the community, we decided to EXTEND the Leaderboard until the final submission deadline.
🗓️ The final submission deadline is also EXTENDED until Aug 15. The final submission form and details will be posted on the IBIS website in the first half of July, follow our Telegram group and mailing list (see the links at https://ibis.autosome.org).