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5735c7d26c16ec1900b927b2
Kathmandu
Kathmandu has a larger proportion of tea drinkers than coffee drinkers. Tea is widely served but is extremely weak by western standards. It is richer and contains tea leaves boiled with milk, sugar and spices. Alcohol is widely drunk, and there are numerous local variants of alcoholic beverages. Drinking and driving is illegal, and authorities have a zero tolerance policy. Ailaa and thwon (alcohol made from rice) are the alcoholic beverages of Kathmandu, found in all the local bhattis (alcohol serving eateries). Chhyaang, tongba (fermented millet or barley) and rakshi are alcoholic beverages from other parts of Nepal which are found in Kathmandu. However, shops and bars in Kathmandu widely sell western and Nepali beers.
What are bhattis?
{ "text": [ "alcohol serving eateries" ], "answer_start": [ 491 ] }
5735c7d26c16ec1900b927b3
Kathmandu
Kathmandu has a larger proportion of tea drinkers than coffee drinkers. Tea is widely served but is extremely weak by western standards. It is richer and contains tea leaves boiled with milk, sugar and spices. Alcohol is widely drunk, and there are numerous local variants of alcoholic beverages. Drinking and driving is illegal, and authorities have a zero tolerance policy. Ailaa and thwon (alcohol made from rice) are the alcoholic beverages of Kathmandu, found in all the local bhattis (alcohol serving eateries). Chhyaang, tongba (fermented millet or barley) and rakshi are alcoholic beverages from other parts of Nepal which are found in Kathmandu. However, shops and bars in Kathmandu widely sell western and Nepali beers.
What goes through a fermentation process to create tongba?
{ "text": [ "millet or barley" ], "answer_start": [ 546 ] }
5735c8876c16ec1900b927be
Kathmandu
Most of the fairs and festivals in Kathmandu originated in the Malla period or earlier. Traditionally, these festivals were celebrated by Newars. In recent years, these festivals have found wider participation from other Kathmanduites as well. As the capital of the Republic of Nepal, various national festivals are celebrated in Kathmandu. With mass migration to the city, the cultures of Khas from the west, Kirats from the east, Bon/Tibetan from the north, and Mithila from the south meet in the capital and mingle harmoniously. The festivities such as the Ghode (horse) Jatra, Indra Jatra, Dashain Durga Puja festivals, Shivratri and many more are observed by all Hindu and Buddhist communities of Kathmandu with devotional fervor and enthusiasm. Social regulation in the codes enacted incorporate Hindu traditions and ethics. These were followed by the Shah kings and previous kings, as devout Hindus and protectors of Buddhist religion.
To what era do a majority of Kathmandu's festivals date back to?
{ "text": [ "Malla" ], "answer_start": [ 63 ] }
5735c8876c16ec1900b927bf
Kathmandu
Most of the fairs and festivals in Kathmandu originated in the Malla period or earlier. Traditionally, these festivals were celebrated by Newars. In recent years, these festivals have found wider participation from other Kathmanduites as well. As the capital of the Republic of Nepal, various national festivals are celebrated in Kathmandu. With mass migration to the city, the cultures of Khas from the west, Kirats from the east, Bon/Tibetan from the north, and Mithila from the south meet in the capital and mingle harmoniously. The festivities such as the Ghode (horse) Jatra, Indra Jatra, Dashain Durga Puja festivals, Shivratri and many more are observed by all Hindu and Buddhist communities of Kathmandu with devotional fervor and enthusiasm. Social regulation in the codes enacted incorporate Hindu traditions and ethics. These were followed by the Shah kings and previous kings, as devout Hindus and protectors of Buddhist religion.
Before the modern era, who mostly celebrated Kathmandu festivals?
{ "text": [ "Newars" ], "answer_start": [ 138 ] }
5735c8876c16ec1900b927c0
Kathmandu
Most of the fairs and festivals in Kathmandu originated in the Malla period or earlier. Traditionally, these festivals were celebrated by Newars. In recent years, these festivals have found wider participation from other Kathmanduites as well. As the capital of the Republic of Nepal, various national festivals are celebrated in Kathmandu. With mass migration to the city, the cultures of Khas from the west, Kirats from the east, Bon/Tibetan from the north, and Mithila from the south meet in the capital and mingle harmoniously. The festivities such as the Ghode (horse) Jatra, Indra Jatra, Dashain Durga Puja festivals, Shivratri and many more are observed by all Hindu and Buddhist communities of Kathmandu with devotional fervor and enthusiasm. Social regulation in the codes enacted incorporate Hindu traditions and ethics. These were followed by the Shah kings and previous kings, as devout Hindus and protectors of Buddhist religion.
In what direction out of Kathmandu did the Khas originate from?
{ "text": [ "west" ], "answer_start": [ 404 ] }
5735c8876c16ec1900b927c1
Kathmandu
Most of the fairs and festivals in Kathmandu originated in the Malla period or earlier. Traditionally, these festivals were celebrated by Newars. In recent years, these festivals have found wider participation from other Kathmanduites as well. As the capital of the Republic of Nepal, various national festivals are celebrated in Kathmandu. With mass migration to the city, the cultures of Khas from the west, Kirats from the east, Bon/Tibetan from the north, and Mithila from the south meet in the capital and mingle harmoniously. The festivities such as the Ghode (horse) Jatra, Indra Jatra, Dashain Durga Puja festivals, Shivratri and many more are observed by all Hindu and Buddhist communities of Kathmandu with devotional fervor and enthusiasm. Social regulation in the codes enacted incorporate Hindu traditions and ethics. These were followed by the Shah kings and previous kings, as devout Hindus and protectors of Buddhist religion.
What does Ghode mean?
{ "text": [ "horse" ], "answer_start": [ 567 ] }
5735c8876c16ec1900b927c2
Kathmandu
Most of the fairs and festivals in Kathmandu originated in the Malla period or earlier. Traditionally, these festivals were celebrated by Newars. In recent years, these festivals have found wider participation from other Kathmanduites as well. As the capital of the Republic of Nepal, various national festivals are celebrated in Kathmandu. With mass migration to the city, the cultures of Khas from the west, Kirats from the east, Bon/Tibetan from the north, and Mithila from the south meet in the capital and mingle harmoniously. The festivities such as the Ghode (horse) Jatra, Indra Jatra, Dashain Durga Puja festivals, Shivratri and many more are observed by all Hindu and Buddhist communities of Kathmandu with devotional fervor and enthusiasm. Social regulation in the codes enacted incorporate Hindu traditions and ethics. These were followed by the Shah kings and previous kings, as devout Hindus and protectors of Buddhist religion.
In relation to Kathmandu, where do the Tibetans hale?
{ "text": [ "north" ], "answer_start": [ 453 ] }
5735c92f012e2f140011a044
Kathmandu
The Bagmati River which flows through Kathmandu is considered a holy river both by Hindus and Buddhists, and many Hindu temples are located on the banks of this river. The importance of the Bagmati also lies in the fact that Hindus are cremated on its banks, and Kirants are buried in the hills by its side. According to the Nepali Hindu tradition, the dead body must be dipped three times into the Bagmati before cremation. The chief mourner (usually the first son) who lights the funeral pyre must take a holy riverwater bath immediately after cremation. Many relatives who join the funeral procession also take bath in the Bagmati River or sprinkle the holy water on their bodies at the end of cremation as the Bagmati is believed to purify people spiritually.
In addition to Hindus, who regards the Bagmati River as sacred?
{ "text": [ "Buddhists" ], "answer_start": [ 94 ] }
5735c92f012e2f140011a045
Kathmandu
The Bagmati River which flows through Kathmandu is considered a holy river both by Hindus and Buddhists, and many Hindu temples are located on the banks of this river. The importance of the Bagmati also lies in the fact that Hindus are cremated on its banks, and Kirants are buried in the hills by its side. According to the Nepali Hindu tradition, the dead body must be dipped three times into the Bagmati before cremation. The chief mourner (usually the first son) who lights the funeral pyre must take a holy riverwater bath immediately after cremation. Many relatives who join the funeral procession also take bath in the Bagmati River or sprinkle the holy water on their bodies at the end of cremation as the Bagmati is believed to purify people spiritually.
What is done with Hindus after they die?
{ "text": [ "cremated" ], "answer_start": [ 236 ] }
5735c92f012e2f140011a046
Kathmandu
The Bagmati River which flows through Kathmandu is considered a holy river both by Hindus and Buddhists, and many Hindu temples are located on the banks of this river. The importance of the Bagmati also lies in the fact that Hindus are cremated on its banks, and Kirants are buried in the hills by its side. According to the Nepali Hindu tradition, the dead body must be dipped three times into the Bagmati before cremation. The chief mourner (usually the first son) who lights the funeral pyre must take a holy riverwater bath immediately after cremation. Many relatives who join the funeral procession also take bath in the Bagmati River or sprinkle the holy water on their bodies at the end of cremation as the Bagmati is believed to purify people spiritually.
What are done with the bodies of Kirants after death?
{ "text": [ "buried" ], "answer_start": [ 275 ] }
5735c92f012e2f140011a047
Kathmandu
The Bagmati River which flows through Kathmandu is considered a holy river both by Hindus and Buddhists, and many Hindu temples are located on the banks of this river. The importance of the Bagmati also lies in the fact that Hindus are cremated on its banks, and Kirants are buried in the hills by its side. According to the Nepali Hindu tradition, the dead body must be dipped three times into the Bagmati before cremation. The chief mourner (usually the first son) who lights the funeral pyre must take a holy riverwater bath immediately after cremation. Many relatives who join the funeral procession also take bath in the Bagmati River or sprinkle the holy water on their bodies at the end of cremation as the Bagmati is believed to purify people spiritually.
In a Hindu funeral, who is typically the main mourner?
{ "text": [ "first son" ], "answer_start": [ 456 ] }
5735c92f012e2f140011a048
Kathmandu
The Bagmati River which flows through Kathmandu is considered a holy river both by Hindus and Buddhists, and many Hindu temples are located on the banks of this river. The importance of the Bagmati also lies in the fact that Hindus are cremated on its banks, and Kirants are buried in the hills by its side. According to the Nepali Hindu tradition, the dead body must be dipped three times into the Bagmati before cremation. The chief mourner (usually the first son) who lights the funeral pyre must take a holy riverwater bath immediately after cremation. Many relatives who join the funeral procession also take bath in the Bagmati River or sprinkle the holy water on their bodies at the end of cremation as the Bagmati is believed to purify people spiritually.
Before Hindus are cremated, how many times are their bodies placed in the Bagmati?
{ "text": [ "three" ], "answer_start": [ 378 ] }
5735c9dd6c16ec1900b927d5
Kathmandu
Legendary Princess Bhrikuti (7th-century) and artist Araniko (1245 - 1306 AD) from that tradition of Kathmandu valley played a significant role in spreading Buddhism in Tibet and China. There are over 108 traditional monasteries (Bahals and Bahis) in Kathmandu based on Newar Buddhism. Since the 1960s, the permanent Tibetan Buddhist population of Kathmandu has risen significantly so that there are now over fifty Tibetan Buddhist monasteries in the area. Also, with the modernization of Newar Buddhism, various Theravada Bihars have been established.
In what century was Bhrikuti said to live?
{ "text": [ "7th" ], "answer_start": [ 29 ] }
5735c9dd6c16ec1900b927d6
Kathmandu
Legendary Princess Bhrikuti (7th-century) and artist Araniko (1245 - 1306 AD) from that tradition of Kathmandu valley played a significant role in spreading Buddhism in Tibet and China. There are over 108 traditional monasteries (Bahals and Bahis) in Kathmandu based on Newar Buddhism. Since the 1960s, the permanent Tibetan Buddhist population of Kathmandu has risen significantly so that there are now over fifty Tibetan Buddhist monasteries in the area. Also, with the modernization of Newar Buddhism, various Theravada Bihars have been established.
When did Araniko die?
{ "text": [ "1306" ], "answer_start": [ 69 ] }
5735c9dd6c16ec1900b927d7
Kathmandu
Legendary Princess Bhrikuti (7th-century) and artist Araniko (1245 - 1306 AD) from that tradition of Kathmandu valley played a significant role in spreading Buddhism in Tibet and China. There are over 108 traditional monasteries (Bahals and Bahis) in Kathmandu based on Newar Buddhism. Since the 1960s, the permanent Tibetan Buddhist population of Kathmandu has risen significantly so that there are now over fifty Tibetan Buddhist monasteries in the area. Also, with the modernization of Newar Buddhism, various Theravada Bihars have been established.
What religion did Araniko help to evangelize?
{ "text": [ "Buddhism" ], "answer_start": [ 157 ] }
5735c9dd6c16ec1900b927d8
Kathmandu
Legendary Princess Bhrikuti (7th-century) and artist Araniko (1245 - 1306 AD) from that tradition of Kathmandu valley played a significant role in spreading Buddhism in Tibet and China. There are over 108 traditional monasteries (Bahals and Bahis) in Kathmandu based on Newar Buddhism. Since the 1960s, the permanent Tibetan Buddhist population of Kathmandu has risen significantly so that there are now over fifty Tibetan Buddhist monasteries in the area. Also, with the modernization of Newar Buddhism, various Theravada Bihars have been established.
How many Newar Buddhist monasteries are present in Kathmandu?
{ "text": [ "108" ], "answer_start": [ 201 ] }
5735c9dd6c16ec1900b927d9
Kathmandu
Legendary Princess Bhrikuti (7th-century) and artist Araniko (1245 - 1306 AD) from that tradition of Kathmandu valley played a significant role in spreading Buddhism in Tibet and China. There are over 108 traditional monasteries (Bahals and Bahis) in Kathmandu based on Newar Buddhism. Since the 1960s, the permanent Tibetan Buddhist population of Kathmandu has risen significantly so that there are now over fifty Tibetan Buddhist monasteries in the area. Also, with the modernization of Newar Buddhism, various Theravada Bihars have been established.
Approximately how many monasteries in the Kathmandu area are run by Tibetan Buddhists?
{ "text": [ "fifty" ], "answer_start": [ 409 ] }
5735ca406c16ec1900b927df
Kathmandu
Kirant Mundhum is one of the indigenous animistic practices of Nepal. It is practiced by Kirat people. Some animistic aspects of Kirant beliefs, such as ancestor worship (worship of Ajima) are also found in Newars of Kirant origin. Ancient religious sites believed to be worshipped by ancient Kirats, such as Pashupatinath, Wanga Akash Bhairabh (Yalambar) and Ajima are now worshipped by people of all Dharmic religions in Kathmandu. Kirats who have migrated from other parts of Nepal to Kathmandu practice Mundhum in the city.
What type of religion is Kirant Mundhum?
{ "text": [ "animistic" ], "answer_start": [ 40 ] }
5735ca406c16ec1900b927e0
Kathmandu
Kirant Mundhum is one of the indigenous animistic practices of Nepal. It is practiced by Kirat people. Some animistic aspects of Kirant beliefs, such as ancestor worship (worship of Ajima) are also found in Newars of Kirant origin. Ancient religious sites believed to be worshipped by ancient Kirats, such as Pashupatinath, Wanga Akash Bhairabh (Yalambar) and Ajima are now worshipped by people of all Dharmic religions in Kathmandu. Kirats who have migrated from other parts of Nepal to Kathmandu practice Mundhum in the city.
Who follows the Kirant Mudhum faith?
{ "text": [ "Kirat people" ], "answer_start": [ 89 ] }
5735ca406c16ec1900b927e1
Kathmandu
Kirant Mundhum is one of the indigenous animistic practices of Nepal. It is practiced by Kirat people. Some animistic aspects of Kirant beliefs, such as ancestor worship (worship of Ajima) are also found in Newars of Kirant origin. Ancient religious sites believed to be worshipped by ancient Kirats, such as Pashupatinath, Wanga Akash Bhairabh (Yalambar) and Ajima are now worshipped by people of all Dharmic religions in Kathmandu. Kirats who have migrated from other parts of Nepal to Kathmandu practice Mundhum in the city.
Who worshipped at Wanga Akash Bhairabh in ancient times?
{ "text": [ "Kirats" ], "answer_start": [ 293 ] }
5735ca406c16ec1900b927e2
Kathmandu
Kirant Mundhum is one of the indigenous animistic practices of Nepal. It is practiced by Kirat people. Some animistic aspects of Kirant beliefs, such as ancestor worship (worship of Ajima) are also found in Newars of Kirant origin. Ancient religious sites believed to be worshipped by ancient Kirats, such as Pashupatinath, Wanga Akash Bhairabh (Yalambar) and Ajima are now worshipped by people of all Dharmic religions in Kathmandu. Kirats who have migrated from other parts of Nepal to Kathmandu practice Mundhum in the city.
What is another name for ancestor worship?
{ "text": [ "worship of Ajima" ], "answer_start": [ 171 ] }
5735cc33012e2f140011a068
Kathmandu
Sikhism is practiced primarily in Gurudwara at Kupundole. An earlier temple of Sikhism is also present in Kathmandu which is now defunct. Jainism is practiced by a small community. A Jain temple is present in Gyaneshwar, where Jains practice their faith. According to the records of the Spiritual Assembly of the Baha'is of Nepal, there are approximately 300 Baha'is in Kathmandu valley. They have a National Office located in Shantinagar, Baneshwor. The Baha'is also have classes for children at the National Centre and other localities in Kathmandu. Islam is practised in Kathmandu but Muslims are a minority, accounting for about 4.2% of the population of Nepal.[citation needed] It is said that in Kathmandu alone there are 170 Christian churches. Christian missionary hospitals, welfare organizations, and schools are also operating. Nepali citizens who served as soldiers in Indian and British armies, who had converted to Christianity while in service, on return to Nepal continue to practice their religion. They have contributed to the spread of Christianity and the building of churches in Nepal and in Kathmandu, in particular.
Where can a temple of the Jain faith be found?
{ "text": [ "Gyaneshwar" ], "answer_start": [ 209 ] }
5735cc33012e2f140011a069
Kathmandu
Sikhism is practiced primarily in Gurudwara at Kupundole. An earlier temple of Sikhism is also present in Kathmandu which is now defunct. Jainism is practiced by a small community. A Jain temple is present in Gyaneshwar, where Jains practice their faith. According to the records of the Spiritual Assembly of the Baha'is of Nepal, there are approximately 300 Baha'is in Kathmandu valley. They have a National Office located in Shantinagar, Baneshwor. The Baha'is also have classes for children at the National Centre and other localities in Kathmandu. Islam is practised in Kathmandu but Muslims are a minority, accounting for about 4.2% of the population of Nepal.[citation needed] It is said that in Kathmandu alone there are 170 Christian churches. Christian missionary hospitals, welfare organizations, and schools are also operating. Nepali citizens who served as soldiers in Indian and British armies, who had converted to Christianity while in service, on return to Nepal continue to practice their religion. They have contributed to the spread of Christianity and the building of churches in Nepal and in Kathmandu, in particular.
Kathmandu valley is home to about how many Baha'i?
{ "text": [ "300" ], "answer_start": [ 355 ] }
5735cc33012e2f140011a06a
Kathmandu
Sikhism is practiced primarily in Gurudwara at Kupundole. An earlier temple of Sikhism is also present in Kathmandu which is now defunct. Jainism is practiced by a small community. A Jain temple is present in Gyaneshwar, where Jains practice their faith. According to the records of the Spiritual Assembly of the Baha'is of Nepal, there are approximately 300 Baha'is in Kathmandu valley. They have a National Office located in Shantinagar, Baneshwor. The Baha'is also have classes for children at the National Centre and other localities in Kathmandu. Islam is practised in Kathmandu but Muslims are a minority, accounting for about 4.2% of the population of Nepal.[citation needed] It is said that in Kathmandu alone there are 170 Christian churches. Christian missionary hospitals, welfare organizations, and schools are also operating. Nepali citizens who served as soldiers in Indian and British armies, who had converted to Christianity while in service, on return to Nepal continue to practice their religion. They have contributed to the spread of Christianity and the building of churches in Nepal and in Kathmandu, in particular.
Where is the Baha'i national office located in Nepal?
{ "text": [ "Shantinagar, Baneshwor" ], "answer_start": [ 427 ] }
5735cc33012e2f140011a06b
Kathmandu
Sikhism is practiced primarily in Gurudwara at Kupundole. An earlier temple of Sikhism is also present in Kathmandu which is now defunct. Jainism is practiced by a small community. A Jain temple is present in Gyaneshwar, where Jains practice their faith. According to the records of the Spiritual Assembly of the Baha'is of Nepal, there are approximately 300 Baha'is in Kathmandu valley. They have a National Office located in Shantinagar, Baneshwor. The Baha'is also have classes for children at the National Centre and other localities in Kathmandu. Islam is practised in Kathmandu but Muslims are a minority, accounting for about 4.2% of the population of Nepal.[citation needed] It is said that in Kathmandu alone there are 170 Christian churches. Christian missionary hospitals, welfare organizations, and schools are also operating. Nepali citizens who served as soldiers in Indian and British armies, who had converted to Christianity while in service, on return to Nepal continue to practice their religion. They have contributed to the spread of Christianity and the building of churches in Nepal and in Kathmandu, in particular.
About what percentage of the Nepali population follows Islam?
{ "text": [ "4.2" ], "answer_start": [ 633 ] }
5735cc33012e2f140011a06c
Kathmandu
Sikhism is practiced primarily in Gurudwara at Kupundole. An earlier temple of Sikhism is also present in Kathmandu which is now defunct. Jainism is practiced by a small community. A Jain temple is present in Gyaneshwar, where Jains practice their faith. According to the records of the Spiritual Assembly of the Baha'is of Nepal, there are approximately 300 Baha'is in Kathmandu valley. They have a National Office located in Shantinagar, Baneshwor. The Baha'is also have classes for children at the National Centre and other localities in Kathmandu. Islam is practised in Kathmandu but Muslims are a minority, accounting for about 4.2% of the population of Nepal.[citation needed] It is said that in Kathmandu alone there are 170 Christian churches. Christian missionary hospitals, welfare organizations, and schools are also operating. Nepali citizens who served as soldiers in Indian and British armies, who had converted to Christianity while in service, on return to Nepal continue to practice their religion. They have contributed to the spread of Christianity and the building of churches in Nepal and in Kathmandu, in particular.
About how many Christian houses of worship exist in Kathmandu?
{ "text": [ "170" ], "answer_start": [ 728 ] }
5735d0026c16ec1900b92815
Kathmandu
Institute of Medicine, the central college of Tribhuwan University is the first medical college of Nepal and is located in Maharajgunj, Kathmandu. It was established in 1972 and started to impart medical education from 1978. A number of medical colleges including Kathmandu Medical College, Nepal Medical College, KIST Medical College, Nepal Army Institute of Health Sciences, National Academy of Medical Sciences (NAMS) and Kathmandu University School of Medical Sciences (KUSMS), are also located in or around Kathmandu.
Of what university is the Institute of Medicine a constituent college?
{ "text": [ "Tribhuwan" ], "answer_start": [ 46 ] }
5735d0026c16ec1900b92816
Kathmandu
Institute of Medicine, the central college of Tribhuwan University is the first medical college of Nepal and is located in Maharajgunj, Kathmandu. It was established in 1972 and started to impart medical education from 1978. A number of medical colleges including Kathmandu Medical College, Nepal Medical College, KIST Medical College, Nepal Army Institute of Health Sciences, National Academy of Medical Sciences (NAMS) and Kathmandu University School of Medical Sciences (KUSMS), are also located in or around Kathmandu.
In what part of Kathmandu is the Institute of Medicine found?
{ "text": [ "Maharajgunj" ], "answer_start": [ 123 ] }
5735d0026c16ec1900b92817
Kathmandu
Institute of Medicine, the central college of Tribhuwan University is the first medical college of Nepal and is located in Maharajgunj, Kathmandu. It was established in 1972 and started to impart medical education from 1978. A number of medical colleges including Kathmandu Medical College, Nepal Medical College, KIST Medical College, Nepal Army Institute of Health Sciences, National Academy of Medical Sciences (NAMS) and Kathmandu University School of Medical Sciences (KUSMS), are also located in or around Kathmandu.
When did the Institute of Medicine begin to offer education in medicine?
{ "text": [ "1978" ], "answer_start": [ 219 ] }
5735d0026c16ec1900b92818
Kathmandu
Institute of Medicine, the central college of Tribhuwan University is the first medical college of Nepal and is located in Maharajgunj, Kathmandu. It was established in 1972 and started to impart medical education from 1978. A number of medical colleges including Kathmandu Medical College, Nepal Medical College, KIST Medical College, Nepal Army Institute of Health Sciences, National Academy of Medical Sciences (NAMS) and Kathmandu University School of Medical Sciences (KUSMS), are also located in or around Kathmandu.
What does KUSMS stand for?
{ "text": [ "Kathmandu University School of Medical Sciences" ], "answer_start": [ 425 ] }
5735d0026c16ec1900b92819
Kathmandu
Institute of Medicine, the central college of Tribhuwan University is the first medical college of Nepal and is located in Maharajgunj, Kathmandu. It was established in 1972 and started to impart medical education from 1978. A number of medical colleges including Kathmandu Medical College, Nepal Medical College, KIST Medical College, Nepal Army Institute of Health Sciences, National Academy of Medical Sciences (NAMS) and Kathmandu University School of Medical Sciences (KUSMS), are also located in or around Kathmandu.
What institution of tertiary education is known as NAMS?
{ "text": [ "National Academy of Medical Sciences" ], "answer_start": [ 377 ] }
5735d07d012e2f140011a087
Kathmandu
Football and Cricket are the most popular sports among the younger generation in Nepal and there are several stadiums in the city. The sport is governed by the All Nepal Football Association (ANFA) from its headquarters in Kathmandu. The only international football stadium in the city is the Dasarath Rangasala Stadium, a multi-purpose stadium used mostly for football matches and cultural events, located in the neighborhood of Tripureshwor. It is the largest stadium in Nepal with a capacity of 25,000 spectators, built in 1956. Martyr's Memorial League is also held in this ground every year. The stadium was renovated with Chinese help before the 8th South Asian Games were held in Kathmandu and had floodlights installed. Kathmandu is home to the oldest football clubs of Nepal such as RCT, Sankata and NRT. Other prominent clubs include MMC, Machhindra FC, Tribhuwan Army Club (TAC) and MPC.
Along with cricket, what sport is highly popular among Nepali youth?
{ "text": [ "Football" ], "answer_start": [ 0 ] }
5735d07d012e2f140011a088
Kathmandu
Football and Cricket are the most popular sports among the younger generation in Nepal and there are several stadiums in the city. The sport is governed by the All Nepal Football Association (ANFA) from its headquarters in Kathmandu. The only international football stadium in the city is the Dasarath Rangasala Stadium, a multi-purpose stadium used mostly for football matches and cultural events, located in the neighborhood of Tripureshwor. It is the largest stadium in Nepal with a capacity of 25,000 spectators, built in 1956. Martyr's Memorial League is also held in this ground every year. The stadium was renovated with Chinese help before the 8th South Asian Games were held in Kathmandu and had floodlights installed. Kathmandu is home to the oldest football clubs of Nepal such as RCT, Sankata and NRT. Other prominent clubs include MMC, Machhindra FC, Tribhuwan Army Club (TAC) and MPC.
What body oversees soccer in Nepal?
{ "text": [ "All Nepal Football Association" ], "answer_start": [ 160 ] }
5735d07d012e2f140011a089
Kathmandu
Football and Cricket are the most popular sports among the younger generation in Nepal and there are several stadiums in the city. The sport is governed by the All Nepal Football Association (ANFA) from its headquarters in Kathmandu. The only international football stadium in the city is the Dasarath Rangasala Stadium, a multi-purpose stadium used mostly for football matches and cultural events, located in the neighborhood of Tripureshwor. It is the largest stadium in Nepal with a capacity of 25,000 spectators, built in 1956. Martyr's Memorial League is also held in this ground every year. The stadium was renovated with Chinese help before the 8th South Asian Games were held in Kathmandu and had floodlights installed. Kathmandu is home to the oldest football clubs of Nepal such as RCT, Sankata and NRT. Other prominent clubs include MMC, Machhindra FC, Tribhuwan Army Club (TAC) and MPC.
How many people can fit in Dasarath Rangasala Stadium?
{ "text": [ "25,000" ], "answer_start": [ 498 ] }
5735d07d012e2f140011a08a
Kathmandu
Football and Cricket are the most popular sports among the younger generation in Nepal and there are several stadiums in the city. The sport is governed by the All Nepal Football Association (ANFA) from its headquarters in Kathmandu. The only international football stadium in the city is the Dasarath Rangasala Stadium, a multi-purpose stadium used mostly for football matches and cultural events, located in the neighborhood of Tripureshwor. It is the largest stadium in Nepal with a capacity of 25,000 spectators, built in 1956. Martyr's Memorial League is also held in this ground every year. The stadium was renovated with Chinese help before the 8th South Asian Games were held in Kathmandu and had floodlights installed. Kathmandu is home to the oldest football clubs of Nepal such as RCT, Sankata and NRT. Other prominent clubs include MMC, Machhindra FC, Tribhuwan Army Club (TAC) and MPC.
In what part of Kathmandu is Dasarath Rangasala Stadium located?
{ "text": [ "Tripureshwor" ], "answer_start": [ 430 ] }
5735d07d012e2f140011a08b
Kathmandu
Football and Cricket are the most popular sports among the younger generation in Nepal and there are several stadiums in the city. The sport is governed by the All Nepal Football Association (ANFA) from its headquarters in Kathmandu. The only international football stadium in the city is the Dasarath Rangasala Stadium, a multi-purpose stadium used mostly for football matches and cultural events, located in the neighborhood of Tripureshwor. It is the largest stadium in Nepal with a capacity of 25,000 spectators, built in 1956. Martyr's Memorial League is also held in this ground every year. The stadium was renovated with Chinese help before the 8th South Asian Games were held in Kathmandu and had floodlights installed. Kathmandu is home to the oldest football clubs of Nepal such as RCT, Sankata and NRT. Other prominent clubs include MMC, Machhindra FC, Tribhuwan Army Club (TAC) and MPC.
Who assisted Nepal in renovating Dasarath Rangasala Stadium?
{ "text": [ "Chinese" ], "answer_start": [ 628 ] }
5735d0f46c16ec1900b92823
Kathmandu
The total length of roads in Nepal is recorded to be (17,182 km (10,676 mi)), as of 2003–04. This fairly large network has helped the economic development of the country, particularly in the fields of agriculture, horticulture, vegetable farming, industry and also tourism. In view of the hilly terrain, transportation takes place in Kathmandu are mainly by road and air. Kathmandu is connected by the Tribhuvan Highway to the south, Prithvi Highway to the west and Araniko Highway to the north. The BP Highway, connecting Kathmandu to the eastern part of Nepal is under construction.
As of 2004, how many kilometers of road existed in Nepal?
{ "text": [ "17,182" ], "answer_start": [ 54 ] }
5735d0f46c16ec1900b92824
Kathmandu
The total length of roads in Nepal is recorded to be (17,182 km (10,676 mi)), as of 2003–04. This fairly large network has helped the economic development of the country, particularly in the fields of agriculture, horticulture, vegetable farming, industry and also tourism. In view of the hilly terrain, transportation takes place in Kathmandu are mainly by road and air. Kathmandu is connected by the Tribhuvan Highway to the south, Prithvi Highway to the west and Araniko Highway to the north. The BP Highway, connecting Kathmandu to the eastern part of Nepal is under construction.
Why is travel in Kathmandu mainly via automobile or aircraft?
{ "text": [ "hilly terrain" ], "answer_start": [ 289 ] }
5735d0f46c16ec1900b92825
Kathmandu
The total length of roads in Nepal is recorded to be (17,182 km (10,676 mi)), as of 2003–04. This fairly large network has helped the economic development of the country, particularly in the fields of agriculture, horticulture, vegetable farming, industry and also tourism. In view of the hilly terrain, transportation takes place in Kathmandu are mainly by road and air. Kathmandu is connected by the Tribhuvan Highway to the south, Prithvi Highway to the west and Araniko Highway to the north. The BP Highway, connecting Kathmandu to the eastern part of Nepal is under construction.
What highway connecting Kathmandu to elsewhere in Nepal is currently being built?
{ "text": [ "BP" ], "answer_start": [ 500 ] }
5735d0f46c16ec1900b92826
Kathmandu
The total length of roads in Nepal is recorded to be (17,182 km (10,676 mi)), as of 2003–04. This fairly large network has helped the economic development of the country, particularly in the fields of agriculture, horticulture, vegetable farming, industry and also tourism. In view of the hilly terrain, transportation takes place in Kathmandu are mainly by road and air. Kathmandu is connected by the Tribhuvan Highway to the south, Prithvi Highway to the west and Araniko Highway to the north. The BP Highway, connecting Kathmandu to the eastern part of Nepal is under construction.
In what direction out of Kathmandu does the Prithvi Highway travel?
{ "text": [ "west" ], "answer_start": [ 457 ] }
5735d0f46c16ec1900b92827
Kathmandu
The total length of roads in Nepal is recorded to be (17,182 km (10,676 mi)), as of 2003–04. This fairly large network has helped the economic development of the country, particularly in the fields of agriculture, horticulture, vegetable farming, industry and also tourism. In view of the hilly terrain, transportation takes place in Kathmandu are mainly by road and air. Kathmandu is connected by the Tribhuvan Highway to the south, Prithvi Highway to the west and Araniko Highway to the north. The BP Highway, connecting Kathmandu to the eastern part of Nepal is under construction.
If one wished to travel north out of Kathmandu, what highway would be used?
{ "text": [ "Araniko" ], "answer_start": [ 466 ] }
5735d1a86c16ec1900b92831
Kathmandu
The main international airport serving Kathmandu and thus Nepal is the Tribhuvan International Airport, located about six kilometers (6 km (3.7 mi)) from the city centre. Operated by the Civil Aviation Authority of Nepal it has two terminals, one domestic and one international. At present, about 22 international airlines connect Nepal to other destinations in Europe, Asia and the Middle East, to cities such as Istanbul, Delhi, Kolkata, Singapore, Bangkok, Kuala Lumpur, Dhaka, Islamabad, Paro, Lhasa, Chengdu, and Guangzhou. A recent extension to the international terminal has made the distance to the airplanes shorter and in October 2009 it became possible to fly directly to Kathmandu from Amsterdam with Arkefly. Since 2013, Turkish Airlines connects Istanbul to Kathmandu. Regionally, several Nepali airlines operate from the city, including Agni Air, Buddha Air, Cosmic Air, Nepal Airlines and Yeti Airlines, to other major towns across Nepal.
What is Nepal's primary airport for international travel?
{ "text": [ "Tribhuvan International Airport" ], "answer_start": [ 71 ] }
5735d1a86c16ec1900b92832
Kathmandu
The main international airport serving Kathmandu and thus Nepal is the Tribhuvan International Airport, located about six kilometers (6 km (3.7 mi)) from the city centre. Operated by the Civil Aviation Authority of Nepal it has two terminals, one domestic and one international. At present, about 22 international airlines connect Nepal to other destinations in Europe, Asia and the Middle East, to cities such as Istanbul, Delhi, Kolkata, Singapore, Bangkok, Kuala Lumpur, Dhaka, Islamabad, Paro, Lhasa, Chengdu, and Guangzhou. A recent extension to the international terminal has made the distance to the airplanes shorter and in October 2009 it became possible to fly directly to Kathmandu from Amsterdam with Arkefly. Since 2013, Turkish Airlines connects Istanbul to Kathmandu. Regionally, several Nepali airlines operate from the city, including Agni Air, Buddha Air, Cosmic Air, Nepal Airlines and Yeti Airlines, to other major towns across Nepal.
Starting in the center of Kathmandu, how many kilometers must one travel to reach Tribhuvan International Airport?
{ "text": [ "6" ], "answer_start": [ 134 ] }
5735d1a86c16ec1900b92833
Kathmandu
The main international airport serving Kathmandu and thus Nepal is the Tribhuvan International Airport, located about six kilometers (6 km (3.7 mi)) from the city centre. Operated by the Civil Aviation Authority of Nepal it has two terminals, one domestic and one international. At present, about 22 international airlines connect Nepal to other destinations in Europe, Asia and the Middle East, to cities such as Istanbul, Delhi, Kolkata, Singapore, Bangkok, Kuala Lumpur, Dhaka, Islamabad, Paro, Lhasa, Chengdu, and Guangzhou. A recent extension to the international terminal has made the distance to the airplanes shorter and in October 2009 it became possible to fly directly to Kathmandu from Amsterdam with Arkefly. Since 2013, Turkish Airlines connects Istanbul to Kathmandu. Regionally, several Nepali airlines operate from the city, including Agni Air, Buddha Air, Cosmic Air, Nepal Airlines and Yeti Airlines, to other major towns across Nepal.
How many airlines use Tribhuvan International for international flights?
{ "text": [ "22" ], "answer_start": [ 297 ] }
5735d1a86c16ec1900b92834
Kathmandu
The main international airport serving Kathmandu and thus Nepal is the Tribhuvan International Airport, located about six kilometers (6 km (3.7 mi)) from the city centre. Operated by the Civil Aviation Authority of Nepal it has two terminals, one domestic and one international. At present, about 22 international airlines connect Nepal to other destinations in Europe, Asia and the Middle East, to cities such as Istanbul, Delhi, Kolkata, Singapore, Bangkok, Kuala Lumpur, Dhaka, Islamabad, Paro, Lhasa, Chengdu, and Guangzhou. A recent extension to the international terminal has made the distance to the airplanes shorter and in October 2009 it became possible to fly directly to Kathmandu from Amsterdam with Arkefly. Since 2013, Turkish Airlines connects Istanbul to Kathmandu. Regionally, several Nepali airlines operate from the city, including Agni Air, Buddha Air, Cosmic Air, Nepal Airlines and Yeti Airlines, to other major towns across Nepal.
From what city does Arkefly offer nonstop flights to Kathmandu?
{ "text": [ "Amsterdam" ], "answer_start": [ 698 ] }
5735d1a86c16ec1900b92835
Kathmandu
The main international airport serving Kathmandu and thus Nepal is the Tribhuvan International Airport, located about six kilometers (6 km (3.7 mi)) from the city centre. Operated by the Civil Aviation Authority of Nepal it has two terminals, one domestic and one international. At present, about 22 international airlines connect Nepal to other destinations in Europe, Asia and the Middle East, to cities such as Istanbul, Delhi, Kolkata, Singapore, Bangkok, Kuala Lumpur, Dhaka, Islamabad, Paro, Lhasa, Chengdu, and Guangzhou. A recent extension to the international terminal has made the distance to the airplanes shorter and in October 2009 it became possible to fly directly to Kathmandu from Amsterdam with Arkefly. Since 2013, Turkish Airlines connects Istanbul to Kathmandu. Regionally, several Nepali airlines operate from the city, including Agni Air, Buddha Air, Cosmic Air, Nepal Airlines and Yeti Airlines, to other major towns across Nepal.
Who operates flights between Kathmandu and Istanbul?
{ "text": [ "Turkish Airlines" ], "answer_start": [ 734 ] }
5735d259012e2f140011a09d
Kathmandu
Kathmandu Metropolitan City (KMC), in order to promote international relations has established an International Relations Secretariat (IRC). KMC's first international relationship was established in 1975 with the city of Eugene, Oregon, United States. This activity has been further enhanced by establishing formal relationships with 8 other cities: Motsumoto City of Japan, Rochester of the USA, Yangon (formerly Rangoon) of Myanmar, Xi'an of the People's Republic of China, Minsk of Belarus, and Pyongyang of the Democratic Republic of Korea. KMC's constant endeavor is to enhance its interaction with SAARC countries, other International agencies and many other major cities of the world to achieve better urban management and developmental programs for Kathmandu.
In what US state did Kathmandu first establish an international relationship?
{ "text": [ "Oregon" ], "answer_start": [ 229 ] }
5735d259012e2f140011a09e
Kathmandu
Kathmandu Metropolitan City (KMC), in order to promote international relations has established an International Relations Secretariat (IRC). KMC's first international relationship was established in 1975 with the city of Eugene, Oregon, United States. This activity has been further enhanced by establishing formal relationships with 8 other cities: Motsumoto City of Japan, Rochester of the USA, Yangon (formerly Rangoon) of Myanmar, Xi'an of the People's Republic of China, Minsk of Belarus, and Pyongyang of the Democratic Republic of Korea. KMC's constant endeavor is to enhance its interaction with SAARC countries, other International agencies and many other major cities of the world to achieve better urban management and developmental programs for Kathmandu.
What was Yangon previously known as?
{ "text": [ "Rangoon" ], "answer_start": [ 414 ] }
5735d259012e2f140011a09f
Kathmandu
Kathmandu Metropolitan City (KMC), in order to promote international relations has established an International Relations Secretariat (IRC). KMC's first international relationship was established in 1975 with the city of Eugene, Oregon, United States. This activity has been further enhanced by establishing formal relationships with 8 other cities: Motsumoto City of Japan, Rochester of the USA, Yangon (formerly Rangoon) of Myanmar, Xi'an of the People's Republic of China, Minsk of Belarus, and Pyongyang of the Democratic Republic of Korea. KMC's constant endeavor is to enhance its interaction with SAARC countries, other International agencies and many other major cities of the world to achieve better urban management and developmental programs for Kathmandu.
With what Belorussian city does Kathmandu have a relationship?
{ "text": [ "Minsk" ], "answer_start": [ 476 ] }
5735d259012e2f140011a0a0
Kathmandu
Kathmandu Metropolitan City (KMC), in order to promote international relations has established an International Relations Secretariat (IRC). KMC's first international relationship was established in 1975 with the city of Eugene, Oregon, United States. This activity has been further enhanced by establishing formal relationships with 8 other cities: Motsumoto City of Japan, Rochester of the USA, Yangon (formerly Rangoon) of Myanmar, Xi'an of the People's Republic of China, Minsk of Belarus, and Pyongyang of the Democratic Republic of Korea. KMC's constant endeavor is to enhance its interaction with SAARC countries, other International agencies and many other major cities of the world to achieve better urban management and developmental programs for Kathmandu.
In what year did Kathmandu create its initial international relationship?
{ "text": [ "1975" ], "answer_start": [ 199 ] }
5735d259012e2f140011a0a1
Kathmandu
Kathmandu Metropolitan City (KMC), in order to promote international relations has established an International Relations Secretariat (IRC). KMC's first international relationship was established in 1975 with the city of Eugene, Oregon, United States. This activity has been further enhanced by establishing formal relationships with 8 other cities: Motsumoto City of Japan, Rochester of the USA, Yangon (formerly Rangoon) of Myanmar, Xi'an of the People's Republic of China, Minsk of Belarus, and Pyongyang of the Democratic Republic of Korea. KMC's constant endeavor is to enhance its interaction with SAARC countries, other International agencies and many other major cities of the world to achieve better urban management and developmental programs for Kathmandu.
What is KMC an initialism of?
{ "text": [ "Kathmandu Metropolitan City" ], "answer_start": [ 0 ] }
5a6b5bfca9e0c9001a4e9f3a
Myocardial_infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.
What is the scientific name for blood flow?
{ "text": [], "answer_start": [] }
5a6b5bfca9e0c9001a4e9f3b
Myocardial_infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.
What percentage of women have had a heart attack?
{ "text": [], "answer_start": [] }
5a6b5bfca9e0c9001a4e9f3c
Myocardial_infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.
What percentage of people have chest pain when experiencing an MI?
{ "text": [], "answer_start": [] }
5a6b5bfca9e0c9001a4e9f3d
Myocardial_infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.
What is heartburn a commonly known as?
{ "text": [], "answer_start": [] }
5a6b5bfca9e0c9001a4e9f3e
Myocardial_infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.
How long does heartburn last?
{ "text": [], "answer_start": [] }
5a6b5d0fa9e0c9001a4e9f44
Myocardial_infarction
Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the complete blockage of a coronary artery caused by a rupture of an atherosclerotic plaque. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.
What is used to confirm a artery spasm?
{ "text": [], "answer_start": [] }
5a6b5d0fa9e0c9001a4e9f45
Myocardial_infarction
Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the complete blockage of a coronary artery caused by a rupture of an atherosclerotic plaque. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.
What test includes cocaine?
{ "text": [], "answer_start": [] }
5a6b5d0fa9e0c9001a4e9f46
Myocardial_infarction
Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the complete blockage of a coronary artery caused by a rupture of an atherosclerotic plaque. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.
What type of rupture helps prevent MI?
{ "text": [], "answer_start": [] }
5a6b5d0fa9e0c9001a4e9f47
Myocardial_infarction
Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the complete blockage of a coronary artery caused by a rupture of an atherosclerotic plaque. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.
What causes extreme cold?
{ "text": [], "answer_start": [] }
5a6b5d0fa9e0c9001a4e9f48
Myocardial_infarction
Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the complete blockage of a coronary artery caused by a rupture of an atherosclerotic plaque. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.
What does a coronary angiography look for?
{ "text": [], "answer_start": [] }
5a6b5ebba9e0c9001a4e9f4e
Myocardial_infarction
Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.
What drugstore item is a poor treatment for MI?
{ "text": [], "answer_start": [] }
5a6b5ebba9e0c9001a4e9f4f
Myocardial_infarction
Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.
Supplemental oxygen does not improve what?
{ "text": [], "answer_start": [] }
5a6b5ebba9e0c9001a4e9f50
Myocardial_infarction
Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.
What medicine is used to remove blockages?
{ "text": [], "answer_start": [] }
5a6b5ebba9e0c9001a4e9f51
Myocardial_infarction
Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.
What surgery is designed to slow blood flow?
{ "text": [], "answer_start": [] }
5a6b5ebba9e0c9001a4e9f52
Myocardial_infarction
Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.
What blood thinner is used in ST elevation treatments?
{ "text": [], "answer_start": [] }
5a6b6844a9e0c9001a4e9f58
Myocardial_infarction
The onset of symptoms in myocardial infarction (MI) is usually gradual, over several minutes, and rarely instantaneous. Chest pain is the most common symptom of acute MI and is often described as a sensation of tightness, pressure, or squeezing. Chest pain due to ischemia (a lack of blood and hence oxygen supply) of the heart muscle is termed angina pectoris. Pain radiates most often to the left arm, but may also radiate to the lower jaw, neck, right arm, back, and upper abdomen, where it may mimic heartburn. Levine's sign, in which a person localizes the chest pain by clenching their fists over their sternum, has classically been thought to be predictive of cardiac chest pain, although a prospective observational study showed it had a poor positive predictive value.
What type of heart problem has a typically instantaneous onset?
{ "text": [], "answer_start": [] }
5a6b6844a9e0c9001a4e9f59
Myocardial_infarction
The onset of symptoms in myocardial infarction (MI) is usually gradual, over several minutes, and rarely instantaneous. Chest pain is the most common symptom of acute MI and is often described as a sensation of tightness, pressure, or squeezing. Chest pain due to ischemia (a lack of blood and hence oxygen supply) of the heart muscle is termed angina pectoris. Pain radiates most often to the left arm, but may also radiate to the lower jaw, neck, right arm, back, and upper abdomen, where it may mimic heartburn. Levine's sign, in which a person localizes the chest pain by clenching their fists over their sternum, has classically been thought to be predictive of cardiac chest pain, although a prospective observational study showed it had a poor positive predictive value.
How is pain in the left arm often described?
{ "text": [], "answer_start": [] }
5a6b6844a9e0c9001a4e9f5a
Myocardial_infarction
The onset of symptoms in myocardial infarction (MI) is usually gradual, over several minutes, and rarely instantaneous. Chest pain is the most common symptom of acute MI and is often described as a sensation of tightness, pressure, or squeezing. Chest pain due to ischemia (a lack of blood and hence oxygen supply) of the heart muscle is termed angina pectoris. Pain radiates most often to the left arm, but may also radiate to the lower jaw, neck, right arm, back, and upper abdomen, where it may mimic heartburn. Levine's sign, in which a person localizes the chest pain by clenching their fists over their sternum, has classically been thought to be predictive of cardiac chest pain, although a prospective observational study showed it had a poor positive predictive value.
What is a good way to predict a heart attack?
{ "text": [], "answer_start": [] }
5a6b6844a9e0c9001a4e9f5b
Myocardial_infarction
The onset of symptoms in myocardial infarction (MI) is usually gradual, over several minutes, and rarely instantaneous. Chest pain is the most common symptom of acute MI and is often described as a sensation of tightness, pressure, or squeezing. Chest pain due to ischemia (a lack of blood and hence oxygen supply) of the heart muscle is termed angina pectoris. Pain radiates most often to the left arm, but may also radiate to the lower jaw, neck, right arm, back, and upper abdomen, where it may mimic heartburn. Levine's sign, in which a person localizes the chest pain by clenching their fists over their sternum, has classically been thought to be predictive of cardiac chest pain, although a prospective observational study showed it had a poor positive predictive value.
What is the term for pain in the left arm?
{ "text": [], "answer_start": [] }
5a6b6844a9e0c9001a4e9f5c
Myocardial_infarction
The onset of symptoms in myocardial infarction (MI) is usually gradual, over several minutes, and rarely instantaneous. Chest pain is the most common symptom of acute MI and is often described as a sensation of tightness, pressure, or squeezing. Chest pain due to ischemia (a lack of blood and hence oxygen supply) of the heart muscle is termed angina pectoris. Pain radiates most often to the left arm, but may also radiate to the lower jaw, neck, right arm, back, and upper abdomen, where it may mimic heartburn. Levine's sign, in which a person localizes the chest pain by clenching their fists over their sternum, has classically been thought to be predictive of cardiac chest pain, although a prospective observational study showed it had a poor positive predictive value.
What does a lack of oxygen supply cause?
{ "text": [], "answer_start": [] }
5a6b69e6a9e0c9001a4e9f62
Myocardial_infarction
Shortness of breath occurs when the damage to the heart limits the output of the left ventricle, causing left ventricular failure and consequent pulmonary edema. Other symptoms include diaphoresis (an excessive form of sweating), weakness, light-headedness, nausea, vomiting, and palpitations. These symptoms are likely induced by a massive surge of catecholamines from the sympathetic nervous system, which occurs in response to pain and the blood flow abnormalities that result from dysfunction of the heart muscle. Loss of consciousness (due to inadequate blood flow to the brain and cardiogenic shock) and sudden death (frequently due to the development of ventricular fibrillation) can occur in MIs.
What is excessive weakness called?
{ "text": [], "answer_start": [] }
5a6b69e6a9e0c9001a4e9f63
Myocardial_infarction
Shortness of breath occurs when the damage to the heart limits the output of the left ventricle, causing left ventricular failure and consequent pulmonary edema. Other symptoms include diaphoresis (an excessive form of sweating), weakness, light-headedness, nausea, vomiting, and palpitations. These symptoms are likely induced by a massive surge of catecholamines from the sympathetic nervous system, which occurs in response to pain and the blood flow abnormalities that result from dysfunction of the heart muscle. Loss of consciousness (due to inadequate blood flow to the brain and cardiogenic shock) and sudden death (frequently due to the development of ventricular fibrillation) can occur in MIs.
Diaphoresis causes a massive surge of what hormones?
{ "text": [], "answer_start": [] }
5a6b69e6a9e0c9001a4e9f64
Myocardial_infarction
Shortness of breath occurs when the damage to the heart limits the output of the left ventricle, causing left ventricular failure and consequent pulmonary edema. Other symptoms include diaphoresis (an excessive form of sweating), weakness, light-headedness, nausea, vomiting, and palpitations. These symptoms are likely induced by a massive surge of catecholamines from the sympathetic nervous system, which occurs in response to pain and the blood flow abnormalities that result from dysfunction of the heart muscle. Loss of consciousness (due to inadequate blood flow to the brain and cardiogenic shock) and sudden death (frequently due to the development of ventricular fibrillation) can occur in MIs.
Which nervous system is responsible for shortness of breath?
{ "text": [], "answer_start": [] }
5a6b69e6a9e0c9001a4e9f65
Myocardial_infarction
Shortness of breath occurs when the damage to the heart limits the output of the left ventricle, causing left ventricular failure and consequent pulmonary edema. Other symptoms include diaphoresis (an excessive form of sweating), weakness, light-headedness, nausea, vomiting, and palpitations. These symptoms are likely induced by a massive surge of catecholamines from the sympathetic nervous system, which occurs in response to pain and the blood flow abnormalities that result from dysfunction of the heart muscle. Loss of consciousness (due to inadequate blood flow to the brain and cardiogenic shock) and sudden death (frequently due to the development of ventricular fibrillation) can occur in MIs.
What is left ventricular failure called?
{ "text": [], "answer_start": [] }
5a6b69e6a9e0c9001a4e9f66
Myocardial_infarction
Shortness of breath occurs when the damage to the heart limits the output of the left ventricle, causing left ventricular failure and consequent pulmonary edema. Other symptoms include diaphoresis (an excessive form of sweating), weakness, light-headedness, nausea, vomiting, and palpitations. These symptoms are likely induced by a massive surge of catecholamines from the sympathetic nervous system, which occurs in response to pain and the blood flow abnormalities that result from dysfunction of the heart muscle. Loss of consciousness (due to inadequate blood flow to the brain and cardiogenic shock) and sudden death (frequently due to the development of ventricular fibrillation) can occur in MIs.
What kind of shock can cause sudden death?
{ "text": [], "answer_start": [] }
5a6b8ce7a9e0c9001a4e9f6c
Myocardial_infarction
Atypical symptoms are more frequently reported by women, the elderly, and those with diabetes when compared to their male and younger counterparts. Women also report more numerous symptoms compared with men (2.6 on average vs. 1.8 symptoms in men). The most common symptoms of MI in women include dyspnea, weakness, and fatigue. Fatigue, sleep disturbances, and dyspnea have been reported as frequently occurring symptoms that may manifest as long as one month before the actual clinically manifested ischemic event. In women, chest pain may be less predictive of coronary ischemia than in men. Women may also experience back or jaw pain during an episode.
How many symptoms do people with diabetes typically report?
{ "text": [], "answer_start": [] }
5a6b8ce7a9e0c9001a4e9f6d
Myocardial_infarction
Atypical symptoms are more frequently reported by women, the elderly, and those with diabetes when compared to their male and younger counterparts. Women also report more numerous symptoms compared with men (2.6 on average vs. 1.8 symptoms in men). The most common symptoms of MI in women include dyspnea, weakness, and fatigue. Fatigue, sleep disturbances, and dyspnea have been reported as frequently occurring symptoms that may manifest as long as one month before the actual clinically manifested ischemic event. In women, chest pain may be less predictive of coronary ischemia than in men. Women may also experience back or jaw pain during an episode.
What are the most common symptoms for men?
{ "text": [], "answer_start": [] }
5a6b8ce7a9e0c9001a4e9f6e
Myocardial_infarction
Atypical symptoms are more frequently reported by women, the elderly, and those with diabetes when compared to their male and younger counterparts. Women also report more numerous symptoms compared with men (2.6 on average vs. 1.8 symptoms in men). The most common symptoms of MI in women include dyspnea, weakness, and fatigue. Fatigue, sleep disturbances, and dyspnea have been reported as frequently occurring symptoms that may manifest as long as one month before the actual clinically manifested ischemic event. In women, chest pain may be less predictive of coronary ischemia than in men. Women may also experience back or jaw pain during an episode.
How long after the ischemic event do symptoms manifest?
{ "text": [], "answer_start": [] }
5a6b8ce7a9e0c9001a4e9f6f
Myocardial_infarction
Atypical symptoms are more frequently reported by women, the elderly, and those with diabetes when compared to their male and younger counterparts. Women also report more numerous symptoms compared with men (2.6 on average vs. 1.8 symptoms in men). The most common symptoms of MI in women include dyspnea, weakness, and fatigue. Fatigue, sleep disturbances, and dyspnea have been reported as frequently occurring symptoms that may manifest as long as one month before the actual clinically manifested ischemic event. In women, chest pain may be less predictive of coronary ischemia than in men. Women may also experience back or jaw pain during an episode.
What is more predictive of coronary ischemia for women?
{ "text": [], "answer_start": [] }
5a6b8d93a9e0c9001a4e9f74
Myocardial_infarction
At least one quarter of all MIs are silent, without chest pain or other symptoms. These cases can be discovered later on electrocardiograms, using blood enzyme tests, or at autopsy without a prior history of related complaints. Estimates of the prevalence of silent MIs vary between 22 and 64%. A silent course is more common in the elderly, in people with diabetes mellitus and after heart transplantation, probably because the donor heart is not fully innervated by the nervous system of the recipient. In people with diabetes, differences in pain threshold, autonomic neuropathy, and psychological factors have been cited as possible explanations for the lack of symptoms.
What percentage of silent cases are later discovered on electrocardiograms?
{ "text": [], "answer_start": [] }
5a6b8d93a9e0c9001a4e9f75
Myocardial_infarction
At least one quarter of all MIs are silent, without chest pain or other symptoms. These cases can be discovered later on electrocardiograms, using blood enzyme tests, or at autopsy without a prior history of related complaints. Estimates of the prevalence of silent MIs vary between 22 and 64%. A silent course is more common in the elderly, in people with diabetes mellitus and after heart transplantation, probably because the donor heart is not fully innervated by the nervous system of the recipient. In people with diabetes, differences in pain threshold, autonomic neuropathy, and psychological factors have been cited as possible explanations for the lack of symptoms.
People with what disease are least likely to experience a silent MI?
{ "text": [], "answer_start": [] }
5a6b8d93a9e0c9001a4e9f76
Myocardial_infarction
At least one quarter of all MIs are silent, without chest pain or other symptoms. These cases can be discovered later on electrocardiograms, using blood enzyme tests, or at autopsy without a prior history of related complaints. Estimates of the prevalence of silent MIs vary between 22 and 64%. A silent course is more common in the elderly, in people with diabetes mellitus and after heart transplantation, probably because the donor heart is not fully innervated by the nervous system of the recipient. In people with diabetes, differences in pain threshold, autonomic neuropathy, and psychological factors have been cited as possible explanations for the lack of symptoms.
Why is a donor heart more sensitive to pain from MIs?
{ "text": [], "answer_start": [] }
5a6b8d93a9e0c9001a4e9f77
Myocardial_infarction
At least one quarter of all MIs are silent, without chest pain or other symptoms. These cases can be discovered later on electrocardiograms, using blood enzyme tests, or at autopsy without a prior history of related complaints. Estimates of the prevalence of silent MIs vary between 22 and 64%. A silent course is more common in the elderly, in people with diabetes mellitus and after heart transplantation, probably because the donor heart is not fully innervated by the nervous system of the recipient. In people with diabetes, differences in pain threshold, autonomic neuropathy, and psychological factors have been cited as possible explanations for the lack of symptoms.
What have been ruled out as possible explanations for silent MIs in diabetics?
{ "text": [], "answer_start": [] }
5a6b8d93a9e0c9001a4e9f78
Myocardial_infarction
At least one quarter of all MIs are silent, without chest pain or other symptoms. These cases can be discovered later on electrocardiograms, using blood enzyme tests, or at autopsy without a prior history of related complaints. Estimates of the prevalence of silent MIs vary between 22 and 64%. A silent course is more common in the elderly, in people with diabetes mellitus and after heart transplantation, probably because the donor heart is not fully innervated by the nervous system of the recipient. In people with diabetes, differences in pain threshold, autonomic neuropathy, and psychological factors have been cited as possible explanations for the lack of symptoms.
What fraction of MIs are discovered with blood enzyme tests?
{ "text": [], "answer_start": [] }
5a6b9825a9e0c9001a4e9f92
Myocardial_infarction
Tobacco smoking (including secondhand smoke) and short-term exposure to air pollution such as carbon monoxide, nitrogen dioxide, and sulfur dioxide (but not ozone) have been associated with MI. Other factors that increase the risk of MI and are associated with worse outcomes after an MI include lack of physical activity and psychosocial factors including low socioeconomic status, social isolation, and negative emotions. Shift work is also associated with a higher risk of MI. Acute and prolonged intake of high quantities of alcoholic drinks (3-4 or more) increase the risk of a heart attack.
What forms of air pollution does smoking tobacco cause?
{ "text": [], "answer_start": [] }
5a6b9825a9e0c9001a4e9f93
Myocardial_infarction
Tobacco smoking (including secondhand smoke) and short-term exposure to air pollution such as carbon monoxide, nitrogen dioxide, and sulfur dioxide (but not ozone) have been associated with MI. Other factors that increase the risk of MI and are associated with worse outcomes after an MI include lack of physical activity and psychosocial factors including low socioeconomic status, social isolation, and negative emotions. Shift work is also associated with a higher risk of MI. Acute and prolonged intake of high quantities of alcoholic drinks (3-4 or more) increase the risk of a heart attack.
How many cigarettes per day increase the risk of a heart attack?
{ "text": [], "answer_start": [] }
5a6b9825a9e0c9001a4e9f94
Myocardial_infarction
Tobacco smoking (including secondhand smoke) and short-term exposure to air pollution such as carbon monoxide, nitrogen dioxide, and sulfur dioxide (but not ozone) have been associated with MI. Other factors that increase the risk of MI and are associated with worse outcomes after an MI include lack of physical activity and psychosocial factors including low socioeconomic status, social isolation, and negative emotions. Shift work is also associated with a higher risk of MI. Acute and prolonged intake of high quantities of alcoholic drinks (3-4 or more) increase the risk of a heart attack.
Increased physical activity is bad for what?
{ "text": [], "answer_start": [] }
5a6b9825a9e0c9001a4e9f95
Myocardial_infarction
Tobacco smoking (including secondhand smoke) and short-term exposure to air pollution such as carbon monoxide, nitrogen dioxide, and sulfur dioxide (but not ozone) have been associated with MI. Other factors that increase the risk of MI and are associated with worse outcomes after an MI include lack of physical activity and psychosocial factors including low socioeconomic status, social isolation, and negative emotions. Shift work is also associated with a higher risk of MI. Acute and prolonged intake of high quantities of alcoholic drinks (3-4 or more) increase the risk of a heart attack.
Short term exposure to 3-4 servings of what is dangerous?
{ "text": [], "answer_start": [] }
5a6b98aca9e0c9001a4e9f9a
Myocardial_infarction
The evidence for saturated fat is unclear. Some state there is evidence of benefit from reducing saturated fat, specifically a benefit from eating polyunsaturated fat instead of saturated fat. While others state there is little evidence that reducing dietary saturated fat or increasing polyunsaturated fat intake affects heart attack risk. Dietary cholesterol does not appear to have a significant effect on blood cholesterol and thus recommendations about its consumption may not be needed. Trans fats do appear to increase risk.
Evidence for what product has proven to be unequivocally dangerous?
{ "text": [], "answer_start": [] }
5a6b98aca9e0c9001a4e9f9b
Myocardial_infarction
The evidence for saturated fat is unclear. Some state there is evidence of benefit from reducing saturated fat, specifically a benefit from eating polyunsaturated fat instead of saturated fat. While others state there is little evidence that reducing dietary saturated fat or increasing polyunsaturated fat intake affects heart attack risk. Dietary cholesterol does not appear to have a significant effect on blood cholesterol and thus recommendations about its consumption may not be needed. Trans fats do appear to increase risk.
Study show you should replace polyunsaturated fat with what?
{ "text": [], "answer_start": [] }
5a6b98aca9e0c9001a4e9f9c
Myocardial_infarction
The evidence for saturated fat is unclear. Some state there is evidence of benefit from reducing saturated fat, specifically a benefit from eating polyunsaturated fat instead of saturated fat. While others state there is little evidence that reducing dietary saturated fat or increasing polyunsaturated fat intake affects heart attack risk. Dietary cholesterol does not appear to have a significant effect on blood cholesterol and thus recommendations about its consumption may not be needed. Trans fats do appear to increase risk.
Blood cholesterol has a significant impact on what?
{ "text": [], "answer_start": [] }
5a6b98aca9e0c9001a4e9f9d
Myocardial_infarction
The evidence for saturated fat is unclear. Some state there is evidence of benefit from reducing saturated fat, specifically a benefit from eating polyunsaturated fat instead of saturated fat. While others state there is little evidence that reducing dietary saturated fat or increasing polyunsaturated fat intake affects heart attack risk. Dietary cholesterol does not appear to have a significant effect on blood cholesterol and thus recommendations about its consumption may not be needed. Trans fats do appear to increase risk.
What type of cholesterol requires careful limitations?
{ "text": [], "answer_start": [] }
5a6b98aca9e0c9001a4e9f9e
Myocardial_infarction
The evidence for saturated fat is unclear. Some state there is evidence of benefit from reducing saturated fat, specifically a benefit from eating polyunsaturated fat instead of saturated fat. While others state there is little evidence that reducing dietary saturated fat or increasing polyunsaturated fat intake affects heart attack risk. Dietary cholesterol does not appear to have a significant effect on blood cholesterol and thus recommendations about its consumption may not be needed. Trans fats do appear to increase risk.
Trans what decreases risk?
{ "text": [], "answer_start": [] }
5a6b99eea9e0c9001a4e9fb8
Myocardial_infarction
Genome-wide association studies have found 27 genetic variants that are associated with an increased risk of myocardial infarction. Strongest association of MI has been found with the 9p21 genomic locus, which contains genes CDKN2A & 2B, although the single nucleotide polymorphisms that are implicated are within a non-coding region. The majority of these variants are in regions that have not been previously implicated in coronary artery disease. The following genes have an association with MI: PCSK9, SORT1, MIA3, WDR12, MRAS, PHACTR1, LPA, TCF21, MTHFDSL, ZC3HC1, CDKN2A, 2B, ABO, PDGF0, APOA5, MNF1ASM283, COL4A1, HHIPC1, SMAD3, ADAMTS7, RAS1, SMG6, SNF8, LDLR, SLC5A3, MRPS6, KCNE2.
How many genetic variants are shown to decrease risk of an MI?
{ "text": [], "answer_start": [] }
5a6b99eea9e0c9001a4e9fb9
Myocardial_infarction
Genome-wide association studies have found 27 genetic variants that are associated with an increased risk of myocardial infarction. Strongest association of MI has been found with the 9p21 genomic locus, which contains genes CDKN2A & 2B, although the single nucleotide polymorphisms that are implicated are within a non-coding region. The majority of these variants are in regions that have not been previously implicated in coronary artery disease. The following genes have an association with MI: PCSK9, SORT1, MIA3, WDR12, MRAS, PHACTR1, LPA, TCF21, MTHFDSL, ZC3HC1, CDKN2A, 2B, ABO, PDGF0, APOA5, MNF1ASM283, COL4A1, HHIPC1, SMAD3, ADAMTS7, RAS1, SMG6, SNF8, LDLR, SLC5A3, MRPS6, KCNE2.
PCSK9 is found in what locus?
{ "text": [], "answer_start": [] }
5a6b99eea9e0c9001a4e9fba
Myocardial_infarction
Genome-wide association studies have found 27 genetic variants that are associated with an increased risk of myocardial infarction. Strongest association of MI has been found with the 9p21 genomic locus, which contains genes CDKN2A & 2B, although the single nucleotide polymorphisms that are implicated are within a non-coding region. The majority of these variants are in regions that have not been previously implicated in coronary artery disease. The following genes have an association with MI: PCSK9, SORT1, MIA3, WDR12, MRAS, PHACTR1, LPA, TCF21, MTHFDSL, ZC3HC1, CDKN2A, 2B, ABO, PDGF0, APOA5, MNF1ASM283, COL4A1, HHIPC1, SMAD3, ADAMTS7, RAS1, SMG6, SNF8, LDLR, SLC5A3, MRPS6, KCNE2.
How many genetic variants are in the 9p21 genomic locus?
{ "text": [], "answer_start": [] }
5a6b99eea9e0c9001a4e9fbb
Myocardial_infarction
Genome-wide association studies have found 27 genetic variants that are associated with an increased risk of myocardial infarction. Strongest association of MI has been found with the 9p21 genomic locus, which contains genes CDKN2A & 2B, although the single nucleotide polymorphisms that are implicated are within a non-coding region. The majority of these variants are in regions that have not been previously implicated in coronary artery disease. The following genes have an association with MI: PCSK9, SORT1, MIA3, WDR12, MRAS, PHACTR1, LPA, TCF21, MTHFDSL, ZC3HC1, CDKN2A, 2B, ABO, PDGF0, APOA5, MNF1ASM283, COL4A1, HHIPC1, SMAD3, ADAMTS7, RAS1, SMG6, SNF8, LDLR, SLC5A3, MRPS6, KCNE2.
What was implicated in the coding region of 9p21?
{ "text": [], "answer_start": [] }
5a6b99eea9e0c9001a4e9fbc
Myocardial_infarction
Genome-wide association studies have found 27 genetic variants that are associated with an increased risk of myocardial infarction. Strongest association of MI has been found with the 9p21 genomic locus, which contains genes CDKN2A & 2B, although the single nucleotide polymorphisms that are implicated are within a non-coding region. The majority of these variants are in regions that have not been previously implicated in coronary artery disease. The following genes have an association with MI: PCSK9, SORT1, MIA3, WDR12, MRAS, PHACTR1, LPA, TCF21, MTHFDSL, ZC3HC1, CDKN2A, 2B, ABO, PDGF0, APOA5, MNF1ASM283, COL4A1, HHIPC1, SMAD3, ADAMTS7, RAS1, SMG6, SNF8, LDLR, SLC5A3, MRPS6, KCNE2.
SORT1 is associated with decreasing risk of what?
{ "text": [], "answer_start": [] }
5a6b9bf84eec6b001a80a4a2
Myocardial_infarction
Acute myocardial infarction refers to two subtypes of acute coronary syndrome, namely non-ST-elevated and ST-elevated MIs, which are most frequently (but not always) a manifestation of coronary artery disease. The most common triggering event is the disruption of an atherosclerotic plaque in an epicardial coronary artery, which leads to a clotting cascade, sometimes resulting in total occlusion of the artery. Atherosclerosis is the gradual buildup of cholesterol and fibrous tissue in plaques in the wall of arteries (in this case, the coronary arteries), typically over decades. Bloodstream column irregularities visible on angiography reflect artery lumen narrowing as a result of decades of advancing atherosclerosis. Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that occludes the artery; this can occur in minutes. When a severe enough plaque rupture occurs in the coronary arteries, it leads to MI (necrosis of downstream myocardium). It is estimated that one billion cardiac cells are lost in a typical MI.
How many subtypes does ST-elevated MI have?
{ "text": [], "answer_start": [] }