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Cessation of D-Pen and the start of corticosteroid therapy were followed by recovery from bicytopenia.
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We report a case of a 60-year-old woman affected by squamous lung carcinoma, who developed paroxysmal supraventricular tachycardia during cisplatin and etoposide combination chemotherapy.
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We describe the development of ischemic colitis in a woman who was treated with tegaserod and review the relationship among ischemic colitis, tegaserod use, and irritable bowel syndrome.
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We report on a 14-year-old boy with severe haemophilia A who developed a portal vein thrombosis during continuous infusion of F VIII.
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Thrombotic thrombocytopenic purpura induced by trimethoprim-sulfamethoxazole in a Jehovah's Witness.
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The natural history of spontaneous coronary artery dissection that persists on angiography after the acute event has not been well characterized.
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RESULTS: Both patients experienced a previously unreported side effect--falling backward--associated with bupropion use.
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Following administration of the antidote, digoxin immune antigen binding fragments (Fab), SDC monitoring is hampered by assay-related problems because of the presence of Fab in the serum.
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CONCLUSIONS: Botulinum toxin injection of the lacrimal gland is an effective palliative treatment for epiphora secondary to canalicular obstruction from docetaxel therapy.
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A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy.
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Acute renal failure with severe tubulointerstitial changes in a patient with minimal change nephrotic syndrome treated with enalapril.
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Persistence of the proximal portion of the right umbilical vein is described in a premature infant.
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PWO is a common problem encountered with VADs.
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A purulent exudate was aspirated from the abscesses under computed tomographic guidance.
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Successful treatment of the fungal infection was achieved using ketoconazole.
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Four patients with similar clinical and laboratory characteristics to our patient's after the combined use of colchicine and statins have been described in the literature.
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Characteristic angiitis was found in the ileum with normal-like mucosa, and it was not necessarily associated with ileal ulcers.
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Allopurinol may be an effective treatment for granulomatous reactions to foreign body particles.
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RESULTS: A previously healthy 42-year-old woman presented with acute-onset delirium with psychotic features as a consequence of levofloxacin therapy.
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We report the clinical outcome of liver, heart, and kidney recipients from a single donor.
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It is always good to ask the question, "Will this help my patient live better or longer?" when prescribing a therapy.
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Two days' administration of levomepromazine 100 mg led him to a coma for 2 days.
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On plain X-ray films and CT scans of the abdomen, pancreatic stones began to be dissolved around 8 months of treatment, and diminished in size and number or disappeared in 21 patients (70%) during the mean follow-up period of 32 months.
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We conclude that metamizole use is common and may be underrecognized in immigrant Latino patients.
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Prior to abdominal closure, he developed copious pulmonary secretions, hypoxemia, and hypotension.
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The toxic effects of methotrexate included elevated liver transaminases (3/4), nausea (2/4), abdominal pain (2/4), bone pain (2/4), mild neutropenia (1/4), and mild pruritus (1/4).
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While undergoing treatment with albendazole, he developed worsening diarrhea with abdominal pain and fever.
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Nimodipine, now widely used for treatment and prevention of cerebrovascular spasm, is regarded as a safe drug.
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Twenty-one days after starting antiretroviral treatment, he became increasingly manic.
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Delayed neurotoxicity of intraventricular interleukin-2: a case report.
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It is usually well tolerated and its application is simple.
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Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin.
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Some of these patients may have been previously treated with radiotherapy.
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None of these patients had had pelvic radiation therapy.
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OBJECTIVE: To report a case of significant hepatic and renal failure with the use of argatroban in a patient with heparin-induced thrombocytopenia (HIT) requiring continuous veno-veno hemodialysis (CVVHD).
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Foscarnet is used as therapy of cytomegalovirus (CMV) infection in immunosuppressed subjects.
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He developed significant ischemic changes in standard 12-lead electrocardiogram, transiently raised cardiac enzymes, reduced left ventricular systolic function, pulmonary edema and pulmonary hemorrhage.
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The patient's methemoglobin level was 63%.
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Impulse control disorders and pathological gambling in patients with Parkinson disease.
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An unusual cause of burn injury: unsupervised use of drugs that contain psoralens.
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RESULTS: Extensive squamous metaplasia was found in endometrial glands following progestin therapy.
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Sudden cardiac arrest associated with major spasm of three coronary arteries was observed about 10 hours after Taxus stent insertion in a three vessel lesion and was successfully treated by intracoronary glyceryl trinitrate infusion.
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Procainamide had no effect upon the defibrillation threshold.
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In the three index patients, the QTc failed to shorten with left stellate ganglion blockade, beta-blocker challenge, or stress testing, suggesting an acquired form of the long QT syndrome in these patients with HIV disease.
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A man with systemic lupus erythematosus receiving chronic steroid therapy presented with headache, fever and panophthalmitis.
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Since elevated cortisol levels in Cushing's disease poses a threat for pancreatitis, there is a possibility that patients with Cushing's disease might be more prone to acute pancreatitis following propofol administration.
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A 22-year-old black man developed fever, chills, fatigue, night sweats, tender lymphadenopathy, and a generalized, pruritic, macular eruption 3 weeks after starting minocycline therapy for acne.
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Dose and a hypersensitivity reaction were doubtful factors in these cases.
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No explanation for this delay was found, other than the possibility that magnesium sulfate treatment impeded lactogenesis.
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Even though anti-inflammatory, analgesic and antipyretic effects of henna have been shown, it may cause severe side-effects in some cases.
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Based on the Naranjo probability scale, serotonin syndrome was a probable adverse reaction associated with co-administration of citalopram and fentanyl.
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Intravenous verapamil therapy in babies may cause apnea, hypotension, and bradycardia; continued episodes of atrial flutter in a child may cause sudden death; quinidine may be related to the death; children with "familial seizure disorders" may in fact have the long QT interval syndrome.
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Hepatic failure developed after a routine surgical procedure.
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Patients with low or absent thiopurine S-methyltransferase (TPMT) activity, resulting in high 6-thioguanine nucleotide levels, have an increased risk of developing leukopenia.
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Temporary suspension of anticoagulant therapy (83% in our study group) to rule out minor surgery, appears to be the most frequent cause of thrombosis.
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In case no. 2, the pathogenic mechanism seemed to be persistent light reaction preceded by systemic photoallergy, as he had taken mequitazine for 6 months, and there were strong positive photopatch test results with immediate erythema reaction, cross-reaction to promethazine, decreased MED to both UVA and UVB, and persistence of the photosensitivity over a 3-year follow-up period after discontinuation of the mequitazine.
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Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin.
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However, correction of the hemodynamic parameters did not improve renal function.
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Protocols that successfully incorporate platinum agents, despite a platinum hypersensitivity, are clinically relevant.
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Acute onset of nephrotic syndrome during interferon-alpha retreatment for chronic active hepatitis C.
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When renal function is compromised, careful monitoring of electrolyte levels, daily urine output, and renal function is necessary with mannitol therapy.
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Two weeks after stopping the adminsitration of tacrolimus, his urine output improved, and the hemoglobin and serum creatinine normalized.
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A 56-year-old woman with scleroderma developed rapidly progressive glomerulonephritis with epithelial crescents associated with hemoptysis after 27 months of D-penicillamine therapy and a cumulative dose of 1,200 g.
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Ventricular free wall rupture remains the most serious complication after acute myocardial infarction.
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He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.
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We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure.
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The epivodes of NMS occured under treatment with clozapine, risperidone, and amisulpride.
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The patient had suffered two spontaneous left humeral fractures treated with prosthesis replacement just before the initial diagnosis of multiple myeloma.
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Four years later, the patient is alive and well with an ejection fraction of 53%.
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OBJECTIVE: To describe a case of thrombocytopenia associated with the administration of lansoprazole.
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It may induce rapid apoptosis and subsequent tumor lysis syndrome.
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The possible relationship with prior and present antiretroviral treatment, and with the most recent literature evidences published in both adults and children with HIV disease are discussed, in order to focus these emerging adverse effects of long-term antiretroviral therapy in the paediatric population, and stimulate further investigation in this field.
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The purpose of this study was to heighten awareness of a potentially life-threatening drug interaction in patients with chronic uveitis treated with cyclosporine.
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Genetic defects of sertraline demethylation and/or Pglycoprotein binding or concurrent circumstances may explain the onset of rhabdomyolysis in this particular patient.
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Reversal of CNS-prophylaxis-related leukoencephalopathy after CSF shunting: case histories of identical twins.
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Leukopenia during thiopurine therapy not explained by TPMT deficiency could be induced by parvovirus B19 infection and compels temporal but not permanent cessation of thiopurine therapy.
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BACKGROUND: Methotrexate (MTX) may induce liver damage, which in some psoriatics will lead to fibrosis or cirrhosis.
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METHODS AND RESULTS: Clinical signs of adrenal suppression were observed in the newborn 3 h after birth.
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There months following surgery, liver metastases were documented associated with elevated levels of serum androgens.
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He was diagnosed with possible serotonin syndrome; his symptoms resolved after clomipramine was stopped but before clozapine was restarted eight days later.
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A 58-yr-old male patient with essential thrombocythaemia (ET) developed chronic myeloid leukaemia (CML) after continuous uneventful treatment with hydroxyurea for 18 yr.
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Our report suggested that CBDCA hypersensitivity was correlated with the total dose of previously administered platinum agents and that CBDCA should be excluded in patients who have received multiple platinum-based chemotherapy, even in platinum-sensitive cases, because CBDCA hypersensitivity can occur even with low-dose CBDCA administration.
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CONCLUSION: It is suggested that antibiotic-induced endotoxemia of a patient with septic endogenous endophthalmitis produced endotoxin-induced uveitis under an upregulation of HLA and endotoxin activated macrophages may release cytokines, followed by fibrin formation and subsequent granuloma.
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This case is reported here for documentation because of its rarity.
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These differences necessitate close monitoring of hypothyroid patients, counseling these patients about the clinical signs of sub- and supratherapeutic levothyroxine dosages, and prudence when switching patients with stable hypothyroidism to alternative levothyroxine products.
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It completely remitted following withdrawal of phenelzine combined with a low dose of haloperidol (1 mg/day) for several days.
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Bilateral Acanthamoeba keratitis with late recurrence of the infection in a corneal graft: a case report.
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Heparin-induced thrombocytopenia complicated with massive thrombosis of the inferior vena cava after filter placement.
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In addition, by far the majority of bleeding complications can be treated effectively.
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Decreased cellular Mg content with normal serum Mg level predisposes to digitalis-toxic arrhythmias.
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The literature is reviewed, and clinical symptoms, pathophysiology, and treatment options are discussed.
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A mere hypoperfusion of the kidney does not seem sufficient to account for all 5 observations: in 3 of them changes in blood pressure did not parallel changes in renal function.
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No adverse effects were observed.
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Patients typically have generalized lymphadenopathy, fever, weight loss, skin rash, polyclonal hypergammaglobulinemia and autoimmune phenomena, and are susceptible to infections.
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The patient has since required a maintenance dose of L-thyroxin.
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The mechanism by which these eruptions occur is not completely understood, although there are many interesting theories.
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OBJECTIVE: We report an adult case of nasopharyngeal carcinoma treated with radical chemo-radiotherapy, with subsequent development of a histologically proved temporal cavernous haemangioma within the radiation field.
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Similar to antiarrhythmic drugs aggravating particular arrhythmias, antiepileptic drugs can paradoxically induce new seizure types or exacerbate existing ones.
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Thus, we suggest that a hypercoagulable status possibly created by both the malignancy and cisplatin-based chemotherapy may have played a significant role in the development of the aortic thrombus.
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After falling and scraping his left elbow, bacitracin ointment was applied to the wound.
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