text
stringlengths
7
742
label
int64
0
1
label_text
stringclasses
2 values
Tailored therapy of adult acute leukaemia in Jehovah's Witnesses: unjustified reluctance to treat.
0
Not-Related
Most patients were also taking concomitant valproic acid.
0
Not-Related
Eruptive latent metastatic melanomas after initiation of antitumor necrosis factor therapies.
0
Not-Related
This complication of insulin therapy was common in the past with the use of animal insulins and became less common with the increasing purification of these and the introduction of recombinant human insulin.
0
Not-Related
This idea should be revised because functional imaging showed that this RLS patient had no dopamine depletion.
0
Not-Related
PATIENTS: Two patients, ages 40 and 51 years, undergoing treatment with interferon alfa for malignant neoplasms experienced sudden bilateral, sequential visual loss with disc-related field defects and segmental optic disc edema.
1
Related
Further post-marketing surveys are required.
0
Not-Related
Fulminant hepatitis associated with disulfiram.
1
Related
However, a new episode of neutropenia, with a WBC count of 2.8 x 10(3)/mm3 and ANC of 0.448 x 10(3)/mm3, occurred 11 days after teicoplanin initiation.
1
Related
Post cardiac surgery diaphragmatic spasm successfully treated with gabapentin.
0
Not-Related
Hepatobiliary disorders associated with orally administered terbinafine have rarely been reported.
1
Related
The neonate weighed 884 g and died 1 h after birth.
0
Not-Related
Finally, clinicians should not extrapolate the results of the Endophthalmitis Vitrectomy Study to the postfiltration surgery endophthalmitis given the differing pathogenesis and unique spectrum of organisms.
0
Not-Related
The potential for adverse system reactions resulting from topical medications should be considered.
0
Not-Related
Methotrexate pneumonitis in nonsurgical treatment of ectopic pregnancy.
1
Related
We also discuss whether screening for DPD deficiency is warranted to identify patients at risk for severe toxicities from 5-FU treatment.
0
Not-Related
A suspected second episode occurred after subsequent chemotherapy and sargramostim treatment.
0
Not-Related
However, we successfully treated the patient with the antibiotics trimethoprim-sulfamethoxazole (TMP/SMX) and minocycline hydrochloride (MINO), and performed endotoxin-absorbing therapy using polymyxin B (PMX) to remove the endotoxin from Gram-negative bacillus as well as continuous hemodiafiltration (CHDF) to remove inflammatory cytokines.
0
Not-Related
48 h after interrupting treatment, she recovered normal neurological status and 500 mg of valacyclovir every 2 days was effective and well tolerated.
0
Not-Related
A 28-year-old female patient complained of intractable pain in the left arm, shoulder, and back and weakness, numbness, and muscular cramp in the left arm.
0
Not-Related
There was prompt response of oral ketoconazole.
0
Not-Related
The main clinical features of this 58-year-old female patient were laboratory evidence of leucopenia and cholestasis, and biopsy features of fatty liver parenchyma degeneration with granulocytic portal infiltration and bile stasis, demonstrated 20 days after the initiation of antithyroid therapy with 20 mg methimazole daily.
1
Related
It seems likely that these reactions were caused by rifabutin, alone or together with other drugs such as clarithromycin.
0
Not-Related
After rechallenge with monotherapy pegvisomant, however, the hepatic enzyme disturbances reappeared within a few weeks, indicating that most likely pegvisomant alone and not the long-acting somatostatin analog or the combination of these two drugs was responsible for this case of drug-induced hepatitis.
1
Related
In addition, a partial recovery of the scotopic b-wave full-field ERG was noted 19 years after cessation of treatment.
0
Not-Related
We report a 43-year-old woman who developed sore throat, swelling of the lips and oral cavity and dysphagia, 2 weeks after the use of budesonide spray (Budefat) for treatment of bronchial asthma.
1
Related
It is important that physicians be alerted to this serious, potentially lethal, complication, as it is readily reversible if the disulfiram is discontinued and appropriate supportive measures are taken.
0
Not-Related
Intravenous valproate has been suggested for the treatment of status epilepticus in part because of its relatively good cardiovascular safety profile.
0
Not-Related
It draws the clinician's attention to unusual susceptibility to extrapyramidal side effects and suggests that if a child shows this type of susceptibility to one neuroleptic, he/she may react similarly to other neuroleptics as well.
0
Not-Related
The ototoxicity of quinine can accurately be studied with ultrahigh frequency audiometry (up to 20 kHz).
1
Related
Fludarabine monophosphate, a purine analogue is used in the treatment of lymphoid malignancies.
0
Not-Related
METHOD: Report of a case.
0
Not-Related
Ballistic movements due to ischemic infarcts after intravenous heroin overdose: report of two cases.
1
Related
His weekly warfarin dose was increased by approximately 5%, and he was given three fecal occult blood cards.
0
Not-Related
A 26-year-old woman with extra-pulmonary Wegener's granulomatosis was treated with cyclophosphamide for 3.25 years, cumulated dose of 91 g.
0
Not-Related
Agranulocytosis and granulocytopenia associated with quetiapine.
1
Related
At the onset of nephrotic syndrome, the patient remained in a hematological remission.
0
Not-Related
At the time she was taking lithium carbonate 450 mg twice/day.
0
Not-Related
Angioedema and dysphagia caused by contact allergy to inhaled budesonide.
1
Related
We report the first case of an acute flare of eosinophilic cystitis in a 51-year-old woman after bladder instillation with dimethyl sulfoxide (DMSO) for presumed interstitial cystitis.
1
Related
Abrupt, fatal intravascular hemolysis occurred after the third course.
0
Not-Related
He was treated with clindamycin, gentamicin and underwent surgical debridement, but succumbed to other complications.
0
Not-Related
Organic affective psychosis associated with the routine use of non-prescription cold preparations.
0
Not-Related
Proliferation of abnormal bone marrow histiocytes, an undesired effect of granulocyte macrophage-colony-stimulating factor therapy in a patient with Hurler's syndrome undergoing bone marrow transplantation.
1
Related
Central nervous system (CNS) toxicity other than optic neuropathy is not widely reported.
0
Not-Related
We describe a first case of keratitis caused by Nocardia exalbida.
0
Not-Related
Seven days later, she had full-blown, severe hepatitis.
0
Not-Related
Our cases constitute the most severe cases of benzarone hepatotoxicity reported so far, and comprise the first cases of (sub)fulminant hepatitis and cirrhosis related to benzarone.
1
Related
MAIN OUTCOME MEASURES: The infants were monitored by serial measurements of basal serum cortisol concentrations, responses to the Synacthen stimulation test, measurement of growth and of weight gain, and, in one case, more detailed anthropometric measures of body composition.
0
Not-Related
We report a case of a patient with mild chronic renal insufficiency who had been taking simvastatin for over a year and developed acute weakness within 3 weeks after the start of treatment with colchicine for acute gouty bursitis.
1
Related
RESULTS: Expression of SSTR2A and PPAR gamma was identified in TSHoma cells.
0
Not-Related
Pulsed-field gel electrophoresis (PFGE) was used to determine whether the isolated microorganisms were the same.
0
Not-Related
A patient is presented with typical hyperthyroidism, who developed a severe proximal muscle weakness and a raised creatine phosphokinase after treatment for hyperthyroidism with propylthiouracil (100 mg orally, three times a day).
1
Related
Thrombolytic therapy with tissue plasminogen activator (tPA) for acute myocardial infarction may result in major bleeding complications such as gastrointestinal or intracranial bleeding.
1
Related
Steroid creams applied topically to the skin are routinely used in the treatment of many dermatoses.
0
Not-Related
Antithyroid treatment with propylthiouracil (PTU) resulted in elevated hepatic enzymes and after the 12th week of pregnancy treatment was changed to carbimazole (CBZ).
1
Related
The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) has numerous etiologies, including medical illness, stress, and various pharmacologic agents.
0
Not-Related
We observed transient panhypogammaglobulinaemia in a patient with neuropsychiatric SLE after treatment with prednisolone and cyclophosphamide.
1
Related
A 42-year-old Thai man was administered the combination drugs liponavir/ritonavir and abacavir/lamivudine.
0
Not-Related
Only 1 case has been described in detail, and this had a fatal outcome.
0
Not-Related
CASE DESCRIPTION: A 5-year-old sexually intact male cockatiel was examined because of progressive dyspnea of 1 week's duration.
0
Not-Related
However, there remain questions concerning whether these drugs, especially methimazole (MMI), may be associated with aplasia cutis congenita (ACC) and how best to avoid impairment of fetal thyroid function during their use.
1
Related
Chronic myelogenous leukemia (CML), hepatitis C, and interferon alpha (IFNalpha) have all been associated with renal dysfunction.
1
Related
Five days after discharge he was readmitted for similar symptoms, including an 11.8-kg weight gain.
0
Not-Related
A case of oculogyric crisis induced by metoclopramide is described in this paper.
1
Related
Abscesses of the pterygopalatine fossa are extremely rare.
0
Not-Related
Nonsustained polymorphous ventricular tachycardia during amiodarone therapy for atrial fibrillation complicating cardiomyopathy.
1
Related
Management of cryptococcosis and toxic epidermal necrolysis in a dog.
0
Not-Related
The case presented here provides some insight into the potential efficacy of certain herbs for relieving mild-to-moderate poison ivy dermatitis.
0
Not-Related
Fatal lung fibrosis caused by paclitaxel toxicity has not been reported In this report, we describe the case of a 62-year-old woman who received six cycles of paclitaxel and carboplatin as combination chemotherapy for advanced ovarian cancer.
1
Related
Topiramate is a new anticonvulsant drug recommended for treatment of partial and generalized seizures in children and adults.
0
Not-Related
It is therefore one of the most serious long-term complications of current cancer treatment and is likely to increase as longer survival rates for the primary tumour are achieved.
0
Not-Related
Scleroderma in association with the use of bleomycin: a report of 3 cases.
1
Related
After an initial diagnosis of atypical eating disorder, an upper gastrointestinal study revealed superior mesenteric artery syndrome.
0
Not-Related
After this episode, she showed the rapid destructive stage of the Rett syndrome, i.e., severe psychomotor retardation with loss of speech, peculiar stereotypic hand movements, autistic behavior and seizures.
0
Not-Related
The effect of repeated exposure to specific chemicals on the initiation or progression of mycosis fungoides (MF) remains unsettled.
0
Not-Related
We are concerned that the macular lesion was a retinal toxic effect of gentamicin because of the recent description of similar lesions occurring after the inadvertent intraocular injection of massive doses of this drug.
1
Related
However, we postulate that a delayed perforation of the bladder might occur due to the cytotoxic effect to the bladder tissue of the instilled drugs.
0
Not-Related
We present two cases of anaphylaxis under anaesthesia where return of spontaneous circulation was refractory to epinephrine, but occurred following the administration of the alpha-agonist metaraminol.
1
Related
BACKGROUND: Methotrexate (MTX) may induce liver damage, which in some psoriatics will lead to fibrosis or cirrhosis.
1
Related
Because of life threatening plasma methotrexate (MTX) levels, carboxypeptidase G2 (CPDG2) was administered resulting in a dramatic decrease within 1 hr.
0
Not-Related
Here we describe a clinical case in which time to diagnosis from the onset of peptic symptoms was delayed more than 10 years, in part reflecting symptom masking by continuous prescription of the PPI omeprazole.
0
Not-Related
The patient suffered excessive toxicity with low-dose irinotecan although no functional polymorphism in UGT1A1 was identified.
0
Not-Related
We describe a 12-year-old boy who developed desquamative interstitial pneumonitis and hepatic cirrhosis several years following the onset of ulcerative colitis.
0
Not-Related
This last test was positive.
0
Not-Related
This suggests that UGT1A9 poor metabolizer genotype(s) may be a predisposing factor for COMT inhibitor-induced hepatotoxicity.
0
Not-Related
We postulate that gastritis caused by dexamethasone, mucositis caused by doxorubicin, and the unique anatomic nature of a Meckel diverticulum may have contributed to this extremely unlikely and previously unreported event.
1
Related
We report the case of an 87-year-old white woman with myasthenia gravis who presented with nausea, shortness of breath, azotemia, and hyperkalemia shortly after completing a course of intravenous immunoglobulin (IVIG).
1
Related
In all three patients, HDL cholesterol levels returned to normal following drug withdrawal.
0
Not-Related
We report a case of 48-year-old woman with seizure disorder on divalproex sodium (Depakote) who presented with dyspnea.
1
Related
We present three cases of fatal hepatic necrosis in patients with epilepsy taking anticonvulsants, in which the terminal illness presented as an unusually severe generalized tonic-clonic seizure with failure to regain consciousness.
0
Not-Related
We described a very atypical case of a high stage, high grade endometrial cancer associated with tamoxifen in a 64-year-old woman with a past history of breast cancer.
1
Related
Eventually, both patients were found to have adrenal insufficiency responsible for the fever, which improved after steroid replacement.
0
Not-Related
Phone followup was attempted.
0
Not-Related
Video distraction initially inhibited vomiting but the treatment effects were not maintained.
0
Not-Related
Successful treatment was achieved with partial resection of the posterior mitral valve leaflet and antibiotic therapy.
0
Not-Related
We describe a 57-year-old man with acral erythrocyanosis progressing to acute digital ischemia and gangrene that developed after combined chemotherapy (bleomycin and methotrexate) used to treat a metastatic squamous cell carcinoma of the hypopharynx.
1
Related
Newborn infants are most vulnerable to the development of thrombosis because of the developing neonatal hemostatic system, perinatal risk factors and different types of medical conditions.
0
Not-Related
A 74-year-old patient with idiopathic Parkinson's disease was evaluated for unintended sleep episodes that occurred after long-term treatment with 400 mg/day of L-dopa.
1
Related
Lithium treatment was terminated in 1975 because of lithium intoxication with a diabetes insipidus-like syndrome.
1
Related